Vol 33, No 3 (March 2012) - Acta Pharmacologica Sinica

Zhi-qiang Ling, Chun-jian Qi, Xiao-xiao Lu, Li-juan Qian, Lin-hui Gu, Zhi-guo Zheng, Qiang Zhao, Shi Wang, Xian-hua Fang, Zhi-xing Yang, Jian Yin, Wei-min Mao

Novel microtubule-targeted agent 6-chloro-4-(methoxyphenyl) coumarin induces G₂-M arrest and apoptosis in HeLa cells Pages (407–417)

Yi-ming Ma, Yu-bo Zhou, Chuan-ming Xie, Dong-mei Chen, Jia Li

Thiazolidione derivatives targeting the histidine kinase YycG are effective against both planktonic and biofilm-associated Staphylococcus epidermidis Pages (418–425)

Ren-zheng Huang, Li-kang Zheng, Hua-yong Liu, Bin Pan, Jian Hu, Tao Zhu, Wei Wang, Dan-bin Jiang, Yang Wu, You-cong Wu, Shi-qing Han, Di Qu

Letter

Differential sensitivity of RIP3-proficient and deficient murine fibroblasts to camptothecin anticancer drugs Pages (426–428)

Jin-xue He, Ying-qing Wang, Jian-ming Feng, Jia-xin Li, Lei Xu, Xiao-hua Li, Wei Wang, Xia-juan Huan, Yi Jiang, Bing Yu, Guang Chen, Ze-hong Miao

Vol 33, No 3 (March 2012): Acta Pharmacologica Sinica(Special Feature:G protein-coupled receptors）

*See the special featured articles marked

Editorial

A new era for GPCR research: structures, biology and drug discovery Pages (289-290)

Review

Structure and activation of rhodopsin Pages (291–299)

Structure and mechanism for recognition of peptide hormones by Class B G-protein-coupled receptors Pages (300–311)

Structure and ligand recognition of class C GPCRs Pages (312–323)

Ice breaking in GPCR structural biology Pages (324–334)

β-Adrenergic receptor subtype signaling in heart: From bench to bedside Pages (335–341)

Role of G protein-coupled receptors in inflammation Pages (342–350)

GPCRs and cancer Pages (351–362)

Orphan G protein-coupled receptors (GPCRs): biological functions and potential drug targets Pages (363–371)

Tools for GPCR drug discovery Pages (372–384) Open

Original Article

Rapamycin prevents the mutant huntingtin-suppressed GLT-1 expression in cultured astrocytes Pages (385–392)

High-sodium intake aggravates myocardial injuries induced by aldosterone via oxidative stress in Sprague-Dawley rats Pages (393–400)

Heterogeneity of chemosensitivity in esophageal cancer using ATP-tumor chemosensitivity assay Pages (401–406)

Novel microtubule-targeted agent 6-chloro-4-(methoxyphenyl) coumarin induces G₂-M arrest and apoptosis in HeLa cells Pages (407–417)

Thiazolidione derivatives targeting the histidine kinase YycG are effective against both planktonic and biofilm-associated Staphylococcus epidermidis Pages (418–425)

Letter

Differential sensitivity of RIP3-proficient and deficient murine fibroblasts to camptothecin anticancer drugs Pages (426–428)

Cover Image

Vol 33, No 3 (March 2012): Acta Pharmacologica Sinica(Special Feature:G protein-coupled receptors）

*See the special featured articles marked

Editorial

A new era for GPCR research: structures, biology and drug discovery Pages (289-290)

Review

Structure and activation of rhodopsin Pages (291–299)

Structure and mechanism for recognition of peptide hormones by Class B G-protein-coupled receptors Pages (300–311)

Structure and ligand recognition of class C GPCRs Pages (312–323)

Ice breaking in GPCR structural biology Pages (324–334)

β-Adrenergic receptor subtype signaling in heart: From bench to bedside Pages (335–341)

Role of G protein-coupled receptors in inflammation Pages (342–350)

GPCRs and cancer Pages (351–362)

Orphan G protein-coupled receptors (GPCRs): biological functions and potential drug targets Pages (363–371)

Tools for GPCR drug discovery Pages (372–384) Open

Original Article

Rapamycin prevents the mutant huntingtin-suppressed GLT-1 expression in cultured astrocytes Pages (385–392)

High-sodium intake aggravates myocardial injuries induced by aldosterone via oxidative stress in Sprague-Dawley rats Pages (393–400)

Heterogeneity of chemosensitivity in esophageal cancer using ATP-tumor chemosensitivity assay Pages (401–406)

Novel microtubule-targeted agent 6-chloro-4-(methoxyphenyl) coumarin induces G2-M arrest and apoptosis in HeLa cells Pages (407–417)

Thiazolidione derivatives targeting the histidine kinase YycG are effective against both planktonic and biofilm-associated Staphylococcus epidermidis Pages (418–425)

Letter

Differential sensitivity of RIP3-proficient and deficient murine fibroblasts to camptothecin anticancer drugs Pages (426–428)

Cover Image

Novel microtubule-targeted agent 6-chloro-4-(methoxyphenyl) coumarin induces G₂-M arrest and apoptosis in HeLa cells Pages (407–417)