Vol 33, No 5 (May 2012): Acta Pharmacologica Sinica

Research Highlight

Methylation of FoxO3 regulates neuronal cell death   Pages (577)
Wei-guo Zhu

Original Article

Asiatic acid, a pentacyclic triterpene in Centella asiatica, attenuates glutamate-induced cognitive deficits in mice and apoptosis in SH-SY5Y cells   Pages (578-587)
Min-fang Xu, Yu-yun Xiong, Jian-kang Liu, Jin-jun Qian, Li Zhu, Jing Gao
Associations between personality changes and nucleus accumbens ablation in opioid addicts   Pages (588-593)
Hai-kang Zhao, Chong-wang Chang, Ning Geng, Li Gao, Jing Wang, Xin Wang, Ya-rong Wang, Xue-lian Wang, Guo-dong Gao
Lowering glucose level elevates [Ca2+]i in hypothalamic arcuate nucleus NPY neurons through P/Q-type Ca2+ channel activation and GSK3β inhibition   Pages (594-605)
Yu Chen, Jun Zhou, Na Xie, Chao Huang, Jun-qi Zhang, Zhuang-li Hu, Lan Ni, You Jin, Fang Wang, Jian-guo Chen, Li-hong Long
Breviscapine inhibits high glucose-induced proliferation and migration of cultured vascular smooth muscle cells of rats via suppressing the ERK1/2 MAPK signaling pathway   Pages (606-614)
Meng He, Zhi-min Xue, Juan Li, Bin-quan Zhou
Non-genomic vasorelaxant effects of 17β-estradiol and progesterone in rat aorta are mediated by L-type Ca2+ current inhibition   Pages (615-624)
Elisa Cairrão, Ezequiel Alvarez, João Miguel Carvas, Antonio Jose Santos-Silva, Ignacio Verde
Raisanberine protected pulmonary arterial rings and cardiac myocytes of rats against hypoxia injury by suppressing NADPH oxidase and calcium influx   Pages (625-634)
Jie Gao, Yi-qun Tang, De-zai Dai, Yu-si Cheng, Guo-lin Zhang, Can Zhang, Yin Dai
Inhibition of hypoxia inducible factor-1α ameliorates lung injury induced by trauma and hemorrhagic shock in rats   Pages (635-643)
Hong Jiang, Yan Huang, Hui Xu, Rong Hu, Qi-fang Li
Treatment of 5/6 nephrectomy rats with sulodexide: a novel therapy for chronic renal failure   Pages (644-651)
Ping Li, Lin-lin Ma, Ru-juan Xie, Yuan-sheng Xie, Ri-bao Wei, Min Yin, Jian-zhong Wang, Xiang-mei Chen
Chronic ethanol consumption increases the levels of chemerin in the serum and adipose tissue of humans and rats   Pages (652-659)
Rui-zhen Ren, Xu Zhang, Jin Xu, Hai-qing Zhang, Chun-xiao Yu, Ming-feng Cao, Ling Gao, Qing-bo Guan, Jia-jun Zhao
Contribution of Myostatin gene polymorphisms to normal variation in lean mass, fat mass and peak BMD in Chinese male offspring   Pages (660-667)
Hua Yue, Jin-wei He, Hao Zhang, Chun Wang, Wei-wei Hu, Jie-mei Gu, Yao-hua Ke, Wen-zhen Fu, Yun-qiu Hu, Miao Li, Yu-juan Liu, Song-hua Wu, Zhen-lin Zhang
Sirt1 overexpression protects murine osteoblasts against TNF-α-induced injury in vitro by suppressing the NF-κB signaling pathway   Pages (668-674)
Wei Huang, Wei-lin Shang, Hua-dong Wang, Wen-wen Wu, Shu-xun Hou
FoxM1 mediated resistance to gefitinib in non-smallcell lung cancer cells   Pages (675-681)
Nuo Xu, Xin Zhang, Xun Wang, Hai-yan Ge, Xiao-ying Wang, David Garfield, Ping Yang, Yuan-lin Song, Chun-xue Bai
Celecoxib induces apoptosis and cell-cycle arrest in nasopharyngeal carcinoma cell lines via inhibition of STAT3 phosphorylation   Pages (682-690)
Dong-bo Liu, Guang-yuan Hu, Guo-xian Long, Hong Qiu, Qi Mei, Guo-qing Hu
Hedgehog signaling pathway mediates invasion and metastasis of hepatocellular carcinoma via ERK pathway   Pages (691-700)
Jing-tao Lu, Wen-di Zhao, Wei He, Wei Wei
Prostanoid EP1 receptor as the target of (−)-epigallocatechin-3-gallate in suppressing hepatocellular carcinoma cells in vitro   Pages (701-709)
Juan Jin, Yan Chang, Wei Wei, Yi-fu He, Shan-shan Hu, Di Wang, Yu-jing Wu
Stereoselective binding of mexiletine and ketoprofen enantiomers with human serum albumin domains   Pages (710-716)
Da Shi, Yin-xiu Jin, Yi-hong Tang, Hai-hong Hu, Si-yun Xu, Lu-shan Yu, Hui-di Jiang, Su Zeng