Vol 33, No 7 (July 2012): Acta Pharmacologica Sinica

Research Highlight

Increased asynchronous GABA release causes more inhibition in human epileptic brain?   Pages (859–860)
Qi Fang, Zhong Chen

Original Article

Atorvastatin enhances neurite outgrowth in cortical neurons in vitro via up-regulating the Akt/mTOR and Akt/GSK-3β signaling pathways   Pages (861–872)
Ying Jin, Hai-juan Sui, Yan Dong, Qi Ding, Wen-hui Qu, Sheng-xue Yu, Ying-xin Jin
The mineralocorticoid receptor-p38MAPK-NFκB or ERK-Sp1 signal pathways mediate aldosterone-stimulated inflammatory and profibrotic responses in rat vascular smooth muscle cells   Pages (873–878)
Chuan-jiang Zhu, Qing-qing Wang, Jun-lan Zhou, Han-zhi Liu, Fang Hua, Hong-zheng Yang, Zhuo-wei Hu
Phosphorylation of endothelial NOS contributes to simvastatin protection against myocardial no-reflow and infarction in reperfused swine hearts: partially via the PKA signaling pathway   Pages (879–887)
Xiang-dong Li, Yue-jin Yang, Yong-jian Geng, Jing-lin Zhao, Hai-tao Zhang, Yu-tong Cheng, Yi-ling Wu
Vam3, a derivative of resveratrol, attenuates cigarette smoke-induced autophagy   Pages (888–896)
Ji Shi, Ning Yin, Ling-ling Xuan, Chun-suo Yao, Ai-min Meng, Qi Hou
siRNA against plasminogen activator inhibitor-1 ameliorates bleomycin-induced lung fibrosis in rats   Pages (897–908)
Yan-ping Zhang, Wen-bin Li, Wei-li Wang, Jian Liu, Shu-xia Song, Lin-lin Bai, Yu-yan Hu, Ya-dong Yuan, Min Zhang
Tissue cholesterol content alterations in streptozotocin-induced diabetic rats   Pages (909–917)
Xin-ting Wang, Jia Li, Li Liu, Nan Hu, Shi Jin, Can Liu, Dan Mei, Xiao-dong Liu
Excess genistein suppresses the synthesis of extracellular matrix in female rat mandibular condylar cartilage   Pages (918–923)
Shi-bin Yu, Xiang-hui Xing, Guang-ying Dong, Xi-li Weng, Mei-qing Wang
Efficacy of zoledronic acid in treatment of teoarthritis is dependent on the disease progression stage in rat medial meniscal tear model   Pages (924–934)
De-gang Yu, Bo Yu, Yuan-qing Mao, Xin Zhao, Xiao-qing Wang, Hui-feng Ding, Lei Cao, Guang-wang Liu, Shao-bo Nie, Shen Liu, Zhen-an Zhu
Anisomycin induces glioma cell death via down-regulation of PP2A catalytic subunit in vitro   Pages (935–940)
Jun-yang Li, Jia-yuan Huang, Meng Li, Han Zhang, Biao Xing, Gong Chen, Dong Wei, Pei-yuan Gu, Wei-xing Hu
Arctigenin alleviates ER stress via activating AMPK   Pages (941–952)
Yuan Gu, Xiao-xiao Sun, Ji-ming Ye, Li He, Shou-sheng Yan, Hao-hao Zhang, Li-hong Hu, Jun-ying Yuan, Qiang Yu
The biphasic redox sensing of SENP3 accounts for the HIF-1 transcriptional activity shift by oxidative stress   Pages (953–963)
Ying Wang, Jie Yang, Kai Yang, Hui Cang, Xin-zhi Huang, Hui Li, Jing Yi
Pharmacophore-based virtual screening and density functional theory approach to identifying novel butyrylcholinesterase inhibitors   Pages (964–978)
Sugunadevi Sakkiah, Keun Woo Lee

Letter to the Editor

Pretreatment with IFN-α increases resistance to imatinib mesylate in patients with chronic myelocytic leukemia   Pages (979–980)
Yin Xiao, Hui-hua Hu, Hong-xiang Wang, Xiao-jian Zhu, Ping Zou, Zhi-chao Chen, Zhao-dong Zhong, Wei-ming Li, Yong You