Vol 33, No 12 (December 2012): Acta Pharmacologica Sinica

Review

PI3K and Akt as molecular targets for cancer therapy: current clinical outcomes   Pages (1441-1458)
Ipsita Pal, Mahitosh Mandal

Original Article

L655,240, acting as a competitive BACE1 inhibitor, efficiently decreases β-amyloid peptide production in HEK293-APPswe cells   Pages (1459-1468)
Qin Lu, Wu-yan Chen, Zhi-yuan Zhu, Jing Chen, Ye-chun Xu, Morakot Kaewpet, Vatcharin Rukachaisirikul, Li-li Chen, Xu Shen
Differential effects of short- and long-term zolpidem treatment on recombinant α1β2γ2s subtype of GABAA receptors in vitro   Pages (1469-1476)
Josipa Vlainić, Maja Jazvinšćak Jembrek, Toni Vlainić, Dubravka Švob Štrac, Danka Peričić
Glycyrrhizin protects rat heart against ischemia-reperfusion injury through blockade of HMGB1-dependent phospho-JNK/Bax pathway   Pages (1477-1487)
Chang-lin Zhai, Mei-qi Zhang, Yun Zhang, Hong-xia Xu, Jing-min Wang, Gui-peng An, Yuan-yuan Wang, Li Li
The effect of pinacidil on postshock activation and ventricular defibrillation threshold in canine hearts   Pages (1488-1494)
Qi Jin, Ning Zhang, Jian Zhou, Chang-jian Lin, Yang Pang, Gang Gu, Wei-feng Shen, Li-qun Wu
Effects of propofol on ischemia-induced ventricular arrhythmias and mitochondrial ATP-sensitive potassium channels   Pages (1495-1501)
Qiang Liu, Jun-yan Yao, Cheng Qian, Rong Chen, Xiao-yu Li, Shao-wen Liu, Bao-gui Sun, Long-sheng Song, Jiang Hong
Angiotensin II regulates the LARG/RhoA/MYPT1 axis in rat vascular smooth muscle in vitro   Pages (1502-1510)
Wei-chiao Chiu, Jyh-ming Juang, Shen-nan Chang, Cho-kai Wu, Chia-ti Tsai, Yung-zu Tseng, Fu-tien Chiang
Nuclear translocation of cysteinyl leukotriene receptor 1 is involved in oxygen-glucose deprivation-induced damage to endothelial cells   Pages (1511-1517)
San-hua Fang, Ka-na Lin, Xue-qin Huang, Yun-bi Lu, Wei-ping Zhang, Er-qing Wei
Telmisartan attenuates hepatic fibrosis in bile duct-ligated rats   Pages (1518-1524)
En-tong Yi, Rui-xia Liu, Yan Wen, Cheng-hong Yin
Breast regression protein-39 (BRP-39) promotes dendritic cell maturation in vitro and enhances Th2 inflammation in murine model of asthma   Pages (1525-1532)
Qian Xu, Shou-jie Chai, Ying-ying Qian, Min Zhang, Kai Wang
Amelioration of influenza virus-induced reactive oxygen species formation by epigallocatechin gallate derived from green tea   Pages (1533-1541)
Jia-xin Ling, Fei Wei, Ning Li, Jin-lin Li, Liang-jun Chen, Yuan-yuan Liu, Fan Luo, Hai-rong Xiong, Wei Hou, Zhan-qiu Yang
Betulinic acid inhibits autophagic flux and induces apoptosis in human multiple myeloma cells in vitro   Pages (1542-1548)
Li-jing Yang, Yan Chen, Jing He, Sha Yi, Lu Wen, Jie Zhao, Ben-ping Zhang, Guo-hui Cui
A single-dose toxicity study on non-radioactive iodinated hypericin for a targeted anticancer therapy in mice   Pages (1549-1556)
Jun-jie Li, Marlein Miranda Cona, Yuan-bo Feng, Feng Chen, Guo-zhi Zhang, Xue-bin Fu, Uwe Himmelreich, Raymond Oyen, Alfons Verbruggen, Yi-cheng Ni
N-Propionyl polysialic acid precursor enhances the susceptibility of multiple myeloma to antitumor effect of anti-NprPSA monoclonal antibody   Pages (1557-1562)
Hong Xiong, Ai-bin Liang, Bing Xiu, Jian-fei Fu, Yi Ding, Yu-hua Chen
Association of CYP3A polymorphisms with the pharmacokinetics of cyclosporine A in early post-renal transplant recipients in China   Pages (1563-1570)
Xiang-guang Meng, Cheng-xian Guo, Guo-qing Feng, Ying-chun Zhao, Bo-ting Zhou, Jian-le Han, Xin Chen, Yong Shi, Hong-yao Shi, Ji-ye Yin, Xiang-dong Peng, Qi Pei, Wei Zhang, Guo Wang, Meng He, Min Liu, Jing-ke Yang, Hong-hao Zhou