New omic and network paradigms for deep understanding of therapeutic mechanisms for Fangji of traditional Chinese medicine
Dayue Darrel Duan1,2,
Zhong Wang3,
Yong-yan Wang3
1 Center for Phenomics of Traditional Chinese Medicine/the Affiliated Hospital of Traditional Chinese Medicine, Southwest Medical University, Luzhou 646000, China
2 Department of Pharmacology, University of Nevada Reno School of Medicine, Reno, NV 89557, USA
3 Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China
Correspondence to: Dayue Darrel Duan: dduan@medicine.nevada.edu, Zhong Wang: zhonw@sina.com, Yong-yan Wang: wangyongyan2010@sina.cn,
DOI: 10.1038/aps.2018.42
Abstract
Combination therapy with multi-drug regimen as an integrated intervention of several pharmacological compounds that interact with multiple targets, rather than monotherapy using a single compound that targets at a single molecule, is a common strategy for combating complex disease in both Western and traditional Chinese medicine (TCM)[1-3].
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