Calcium antagonism of allitridi
Abstract
Allitridi inhibited human platelet aggregation induced by calcimycin and significantly decreased tension contraction of rat aortic strips induced by norepinephrine and KCl, caused the dose-response curves of norepinephrine and CaCl2 to shift rightward and depressed the maximal response. The influences of allitridi and verapamil on the dose-response curves of norepinephrine and CaCl2 were similar. The results indicate that allitridi may be a calcium antagonist.
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