Original Article

Cardiovascular effects of kainic acid injected into habenular nucleus

Shao-Nian Yang, Yu-Huan Tang, Shao Wang

Abstract

The present study was to determine if the cardiovascular effect being produced by exciting cells in the habenular nucleus (Hab). Experiments were performed on urethane-anesthetized rats. Microinjection of kainic acid into Hab demonstrated dose-dependent increases in arterial blood pressure and heart rate, accompanied by other sympathetic reactions, such as mydriasis and pilo-erection. But microinjection of lidocaine into Hab did not elicit similar effects mentioned above.
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