Original Article

Triggered activities induced by cesium chloride and terminated by drugs in cat heart in vivo

Cui-Lan Li, Jing-Tian Xie

Abstract

Monophasic action potential (MAP) of the left ventricular epicardium in vivo in 58 cats were recorded by using a contact electrode. The results showed that early after depolarization, delayed after depolarization, oscillatory afterpotential, and some kinds of triggered arrhythmias were induced by CsCl (iv 0.5 mmol.kg-1), that these afterdepolarizations and triggered arrhythmias were prevented by sodium valproate, and that ventricular tachycardias induced by CsCl was terminated by lidocaine, moricizine, and sodium valproate.
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