Original Articles

Pharmacokinetics of vasicine in healthy Indian volunteers

V Amla, G Bano, R K Johri, U Zutshi, C K Atal

Abstract

The pharmacokinetic study of vasicine was conducted on 6 human volunteers after a bolus iv dose of 1.5 mg/kg. The peak plasma concentration of 65±5 μmol/L was obtained at 15 min, and by 4 h only one third of the peak concentration was detected in plasma. These findings correlate well with the clinical studies conducted earlier with vasicine on patients of bronchial asthma.
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