Original Articles

Influences of acetagastrodin on fetuses of mice and rats

Jian-Ming Xiong, Yun-Qiang Mo, Bin Liang, Zhi-He Chen, Shi-Xian Deng

Abstract

After mice and rats were given ig acetagastrodin at the dosage of 373 mg/(kg∙d) during d 6-15 of pregnancy, no obvious influences on fetus’ weight, sex, placenta, appearance, viscera, and skeleton development were found. No obvious influences on formation of fetus organs and teratogeny were found in mice given acetagastrodin at the dosage of 373 and 1490 mg/(kg∙d) or rats at the dosage of 32.3 and 64.5 mg/(kg∙d).
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