Original Articles

Hydrolysis of soman and paraoxon by catalase

Chang-ling Liu, Guo-qing Wang, Ting-chong Zhou

Abstract

Hydrolysis of soman and paraoxon were catalyzed by catalase. The hydrolytic products of soman were hydrofluoric acid(HF) and pinacolyl methylphosphonic acid(PMP),whereas the hydrolytic product of paraoxon was p-nitrophenol.VX was not catalyzed by catalase. The hydrolysis rates of soman by catalase from various source were different. The catalase obtained from bacteria was the most active one.Km of the reaction of catalase with soman was 0.9-1.0 mM.
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