Effect of astragalus polysaccharides on phagocyic function in mice
Abstract
Intraperitoneal injections of the polysaccharids (APS) isolated from Astragalus mongolicus caused an increase in the number of intraperitoneal macrophages and in the ability of phagocytosis of sheep rbc. As seen by scanning electron microscopy the macrophages of the APS group were mostly flattened, while those of the control were mostly spherical. The activated macrophages in the spleen of APS group were also increased. If APS was given iv or ig, even at higher dosages, the phagocytic function of the intraperinoneal macrophages did not change significantly.
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