2021 APS Outstanding Contribution Awards

APS (Acta Pharmacologica Sinica), published monthly in English, is an international peer-reviewed journal. With the leading by Professor Jian Ding, Editor-in-Chief, and the support from a respected global editorial board, APS is continuously growing to a high-level journal in the area of pharmacology and related life sciences. We owe all the journal progress to our authors, reviewers, and guest editors. To acknowledge their fine contributions to the journal, we set awards to outstanding papers, reviewers, and guest editors.

APS Outstanding Paper Award

KLF4 functions as an oncogene in promoting cancer stem cell-like characteristics in osteosarcoma cells
Xiao-Tian Qi, Yang-Ling Li, Yan-Qi Zhang, Tong Xu, Bin Lu, Liang Fang, Jian-Qing Gao, Lu-Shan Yu, Di-Feng Zhu, Bo Yang, Qiao-Jun He, Mei-Dan Ying
Acta Pharmacol Sin. 2019 Apr;40 (4): 546-555. doi: 10.1038/s41401-018-0050-6. Epub 2018 Jun 21.

Ginsenoside Rg1 protects against ischemic/reperfusion-induced neuronal injury through miR-144/Nrf2/ARE pathway
Shi-Feng Chu, Zhao Zhang, Xin Zhou, Wen-Bin He, Chen Chen, Piao Luo, Dan-Dan Liu, Qi-di Ai, Hai-Fan Gong, Zhen-Zhen Wang, Hong-Shuo Sun, Zhong-Ping Feng, Nai-Hong Chen
Acta Pharmacol Sin. 2019 Jan; 40(1): 13-25. doi: 10.1038/s41401-018-0154-z. Epub 2018 Sep 27.

Diterpene ginkgolides protect against cerebral ischemia/reperfusion damage in rats by activating Nrf2 and CREB through PI3K/Akt signaling
Wen Zhang, Jun-Ke Song, Rong Yan, Li Li, Zhi-Yong Xiao, Wen-Xia Zhou, Zhen-Zhong Wang, Wei Xiao, Guan-Hua Du
Acta Pharmacol Sin. 2018 Aug; 39(8): 1259-1272. doi: 10.1038/aps.2017.149. Epub 2018 Mar 15.

HOTAIR lncRNA SNPs rs920778 and rs1899663 are associated with smoking, male gender, and squamous cell carcinoma in a Chinese lung cancer population
Cong Wang, Ying Li, Yong-Wen Li, Hong-Bing Zhang, Hao Gong, Yin Yuan, Wei-Ting Li, Hong-Yu Liu, Jun Chen
Acta Pharmacol Sin. 2018 Nov; 39(11): 1797-1803. doi: 10.1038/s41401-018-0083-x. Epub 2018 Aug 28.

Eukaryotic elongation factor-2 kinase regulates the cross-talk between autophagy and pyroptosis in doxorubicin-treated human melanoma cells in vitro
Pian Yu, Hai-Yan Wang, Min Tian, Ao-Xue Li, Xi-Sha Chen, Xin-Luan Wang, Yi Zhang, Yan Cheng
Acta Pharmacol Sin. 2019 Sep; 40(9): 1237-1244. doi: 10.1038/s41401-019-0222-z. Epub 2019 Mar 26.

Berberine attenuates ischemia-reperfusion injury through inhibiting HMGB1 release and NF-κB nuclear translocation
Jun-Rong Zhu, Hai-Dan Lu, Chao Guo, Wei-Rong Fang, Hong-Dong Zhao, Jun-Shan Zhou, Feng Wang, Yan-Li Zhao, Yun-Man Li, Ying-Dong Zhang, Chang-Qing Yang, Jian-Guo Sun
Acta Pharmacol Sin. 2018 Nov; 39(11): 1706-1715. doi: 10.1038/s41401-018-0160-1.

Artemisinin analogue SM934 ameliorates DSS-induced mouse ulcerative colitis via suppressing neutrophils and macrophages
Yu-Xi Yan, Mei-Juan Shao, Qing Qi, Yan-Sheng Xu, Xiao-Qian Yang, Feng-Hua Zhu, Shi-Jun He, Pei-Lan He, Chun-Lan Feng, Yan-Wei Wu, Heng Li, Wei Tang, Jian-Ping Zuo
Acta Pharmacol Sin. 2018 Oct; 39(10): 1633-1644. doi: 10.1038/aps.2017.185. Epub 2018 May 31.

Cannabidiol does not display drug abuse potential in mice behavior
Adrián Viudez-Martínez, María S García-Gutiérrez, Juan Medrano-Relinque, Carmen M Navarrón, Francisco Navarrete, Jorge Manzanares
Acta Pharmacol Sin. 2019 Mar; 40(3): 358-364. doi: 10.1038/s41401-018-0032-8. Epub 2018 Jul 18.

CTC clusters induced by heparanase enhance breast cancer metastasis
Rong-Rui Wei, Dan-Ni Sun, Hong Yang, Juan Yan, Xiong Zhang, Xing-Ling Zheng, Xu-Hong Fu, Mei-Yu Geng, Xun Huang, Jian Ding
Acta Pharmacol Sin. 2018 Aug; 39(8): 1326-1337. doi: 10.1038/aps.2017.189. Epub 2018 Feb 8.

CP-25 reverses prostaglandin E4 receptor desensitization-induced fibroblast-like synoviocyte dysfunction via the G protein-coupled receptor kinase 2 in autoimmune arthritis
Xiao-Yi Jia, Yan Chang, Fang Wei, Xing Dai, Yu-Jing Wu, Xiao-Jing Sun, Shu Xu, Hua-Xun Wu, Chun Wang, Xue-Zhi Yang, Wei Wei
Acta Pharmacol Sin. 2019 Aug; 40(8): 1029-1039. doi: 10.1038/s41401-018-0196-2. Epub 2019 Jan 14.

Pharmacological activation of REV-ERBα represses LPS-induced microglial activation through the NF-κB pathway
Dong-Kai Guo, Yao Zhu, Hong-Yang Sun, Xing-Yun Xu, Shun Zhang, Zong-Bing Hao, Guang-Hui Wang, Chen-Chen Mu, Hai-Gang Ren
Acta Pharmacol Sin. 2019 Jan; 40(1): 26-34. doi: 10.1038/s41401-018-0064-0. Epub 2018 Jun 27.

Ganoderma lucidum extract ameliorates MPTP-induced parkinsonism and protects dopaminergic neurons from oxidative stress via regulating mitochondrial function, autophagy, and apoptosis
Zhi-Li Ren, Chao-Dong Wang, Tao Wang, Hui Ding, Ming Zhou, Nan Yang, Yan-Yong Liu, Piu Chan
Acta Pharmacol Sin. 2019 Apr; 40(4): 441-450. doi: 10.1038/s41401-018-0077-8. Epub 2018 Jul 10.

Salvia miltiorrhizaBurge (Danshen): a golden herbal medicine in cardiovascular therapeutics
Zhuo-Ming Li, Suo-Wen Xu, Pei-Qing Liu
Acta Pharmacol Sin. 2018 May; 39(5): 802-824. doi: 10.1038/aps.2017.193.

TRPM2: a candidate therapeutic target for treating neurological diseases
Jillian Corinne Belrose, Michael Frederick Jackson
Acta Pharmacol Sin. 2018 May; 39(5): 722-732. doi: 10.1038/aps.2018.31.

GPR3, GPR6, and GPR12 as novel molecular targets: their biological functions and interaction with cannabidiol
Alyssa S Laun, Sarah H Shrader, Kevin J Brown, Zhao-Hui Song
Acta Pharmacol Sin. 2019 Mar; 40(3): 300-308. doi: 10.1038/s41401-018-0031-9. Epub 2018 Jun 25.

Discovery and development of NA-1 for the treatment of acute ischemic stroke
Beatrice Ballarin, Michael Tymianski
Acta Pharmacol Sin. 2018 May; 39(5): 661-668. doi: 10.1038/aps.2018.5. Epub 2018 Mar 22.

Vascular endothelial dysfunction, a major mediator in diabetic cardiomyopathy
Maura Knapp, Xin Tu, Rongxue Wu
Acta Pharmacol Sin. 2019 Jan; 40(1): 1-8. doi: 10.1038/s41401-018-0042-6. Epub 2018 Jun 4.

Heart-type fatty acid binding protein (H-FABP) as a biomarker for acute myocardial injury and long-term post-ischemic prognosis
Xiao-Dong Ye, Yi He, Sheng Wang, Gordon T Wong, Michael G Irwin, Zhengyuan Xia
Acta Pharmacol Sin. 2018 Jul; 39(7): 1155-1163. doi: 10.1038/aps.2018.37. Epub 2018 May 17.

The role of K_ATP channels in cerebral ischemic stroke and diabetes
Vivian Szeto, Nai-Hong Chen, Hong-Shuo Sun, Zhong-Ping Feng
Acta Pharmacol Sin. 2018 May; 39(5): 683-694. doi: 10.1038/aps.2018.10. Epub 2018 Apr 19.

Role of oxylipins in cardiovascular diseases
Mohammed A Nayeem
Acta Pharmacol Sin. 2018 Jul; 39(7): 1142-1154. doi: 10.1038/aps.2018.24. Epub 2018 Jun 7.

MicroRNAs as biomarkers for human glioblastoma: progress and potential
Shi-Wei Huang, Ni-da Ali, Lily Zhong, Jian Shi
Acta Pharmacol Sin. 2018 Sep; 39(9): 1405-1413. doi: 10.1038/aps.2017.173. Epub 2018 Feb 8.

Oncogene-induced senescence: a double edged sword in cancer
Xue-Ling Liu, Jian Ding, Ling-Hua Meng
Acta Pharmacol Sin. 2018 Oct; 39(10): 1553-1558. doi: 10.1038/aps.2017.198. Epub 2018 Apr 5.

Overview of recent advances in liposomal nanoparticle-based cancer immunotherapy
Ang Gao, Xian-Li Hu, Madiha Saeed, Bin-Fan Chen, Ya-Ping Li, Hai-Jun Yu
Acta Pharmacol Sin. 2019 Sep; 40(9): 1129-1137. doi: 10.1038/s41401-019-0281-1. Epub 2019 Aug 1.

APS Outstanding Reviewer Award

 Download PDF